Thomas O Carpenter Selected Research

ectonucleotide pyrophosphatase phosphodiesterase 1

1/2022	Catalysis-Independent ENPP1 Protein Signaling Regulates Mammalian Bone Mass.
1/2022	Musculoskeletal Comorbidities and Quality of Life in ENPP1-Deficient Adults and the Response of Enthesopathy to Enzyme Replacement Therapy in Murine Models.
1/2021	Response of the ENPP1-Deficient Skeletal Phenotype to Oral Phosphate Supplementation and/or Enzyme Replacement Therapy: Comparative Studies in Humans and Mice.

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Thomas O Carpenter Research Topics

Disease

22	Familial Hypophosphatemic Rickets (X-Linked Hypophosphatemia) 01/2022 - 09/2009
20	Rickets (Rachitis) 01/2022 - 03/2001
16	Hypophosphatemia 01/2022 - 03/2001
11	Osteomalacia 01/2022 - 03/2001
8	Hypophosphatemic Rickets 01/2022 - 02/2006
7	Congenital Abnormalities (Deformity) 01/2019 - 02/2006
6	Hypercalciuria 10/2017 - 03/2001
6	Hypercalcemia (Milk Alkali Syndrome) 10/2017 - 07/2005
5	Osteoporosis 01/2022 - 02/2010
5	Pain (Aches) 01/2022 - 02/2006
4	Metabolic Bone Diseases (Osteopenia) 01/2022 - 09/2014
4	Vitamin D Deficiency 07/2021 - 07/2005
4	Nephrocalcinosis 01/2021 - 04/2014
4	Hereditary Hypophosphatemic Rickets with Hypercalciuria 10/2014 - 03/2001
4	Hyperparathyroidism 09/2014 - 07/2005
3	Oncogenic osteomalacia 12/2021 - 02/2005
3	Renal Insufficiency (Renal Failure) 01/2021 - 03/2008
3	Bone Diseases (Bone Disease) 10/2020 - 01/2015
2	Enthesopathy 01/2022 - 10/2015
2	Arterial calcification of infancy 01/2022 - 01/2021
2	Neoplasms (Cancer) 01/2021 - 02/2005
2	Secondary Hyperparathyroidism 10/2019 - 09/2014
2	Inborn Genetic Diseases (Disease, Hereditary) 09/2019 - 07/2005
2	Osteoarthritis 01/2018 - 12/2016
2	Infantile Hypercalcemia 10/2017 - 02/2012
2	Nephrolithiasis 10/2017 - 10/2014
2	Hypocalcemia 01/2017 - 07/2005
2	Muscle Weakness 10/2016 - 02/2006
2	Osteogenesis Imperfecta (Lobstein Disease) 01/2016 - 11/2013
2	type 6 Osteogenesis imperfecta 01/2016 - 11/2013
2	Chronic Kidney Disease-Mineral and Bone Disorder (Renal Rickets) 01/2012 - 03/2008
2	Wasting Syndrome (Wasting Disease) 02/2005 - 03/2001
1	Musculoskeletal Diseases (Musculoskeletal Disease) 01/2022
1	Vascular Calcification 01/2022
1	Chronic Disease (Chronic Diseases) 01/2022
1	Achlorhydria (Hypochlorhydria) 01/2021
1	Fatigue 01/2021
1	Hypophosphatemic Bone Disease 10/2020
1	Headache (Headaches) 01/2020
1	Insulin Resistance 01/2020
1	Leukemia 01/2020
1	Lymphoma (Lymphomas) 01/2020
1	Nausea 01/2020
1	Iron-Deficiency Anemia (Anemia, Iron Deficiency) 01/2020
1	Drug-Related Side Effects and Adverse Reactions 01/2020
1	Body Weight (Weight, Body) 01/2018
1	Arthralgia (Joint Pain) 12/2016
1	Stomatognathic Diseases (Dental Disease) 10/2015
1	Cystic Fibrosis (Mucoviscidosis) 05/2015
1	Acidosis 09/2014

Drug/Important Bio-Agent (IBA)

32	Phosphates (Orthophosphate)IBA 01/2022 - 03/2001
14	Fibroblast Growth Factor-23IBA 01/2022 - 02/2010
13	burosumabIBA 01/2022 - 04/2014
12	Vitamin D FDA LinkGeneric 10/2019 - 08/2003
10	CalciumIBA 10/2019 - 08/2003
8	1,25-dihydroxyvitamin DIBA 04/2016 - 03/2001
7	Monoclonal AntibodiesIBA 01/2022 - 02/2005
6	Phosphorus (Red Phosphorus)IBA 01/2021 - 04/2015
6	Parathyroid Hormone (Parathormone)IBA 01/2020 - 07/2005
5	25-hydroxyvitamin DIBA 05/2015 - 08/2003
4	Proteins (Proteins, Gene)FDA Link 01/2021 - 12/2011
4	MineralsIBA 01/2020 - 07/2005
3	Calcitriol (Calcijex)FDA LinkGeneric 01/2022 - 04/2010
3	EnzymesIBA 01/2022 - 01/2021
3	ectonucleotide pyrophosphatase phosphodiesterase 1IBA 01/2022 - 01/2021
3	Fibroblast Growth Factors (Fibroblast Growth Factor)IBA 01/2020 - 11/2010
3	CreatinineIBA 01/2019 - 04/2014
2	Insulin (Novolin)FDA Link 01/2020 - 10/2016
2	Vitamin D3 24-HydroxylaseIBA 10/2017 - 02/2012
2	SodiumIBA 10/2016 - 10/2014
2	Thymidine Monophosphate (TMP)IBA 02/2016 - 07/2015
2	pigment epithelium-derived factorIBA 01/2016 - 11/2013
1	Analgesics (Analgesic Drugs)IBA 01/2022
1	Cholecalciferol (Vitamin D3)FDA Link 07/2021
1	Esomeprazole (Nexium)FDA Link 01/2021
1	diphosphoric acid (pyrophosphoric acid)IBA 01/2021
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2021
1	Phosphoric Diester Hydrolases (Phosphodiesterases)IBA 01/2021
1	Biomarkers (Surrogate Marker)IBA 01/2020
1	ferric derisomaltoseIBA 01/2020
1	ferric carboxymaltoseIBA 01/2020
1	iron isomaltoside 1000IBA 01/2020
1	Ferritins (Ferritin)IBA 01/2020
1	Hemoglobins (Hemoglobin)IBA 01/2020
1	IronIBA 01/2020
1	dimemorfan (AT 17)IBA 01/2017
1	Amino Acids FDA Link 01/2017
1	Adenosine Triphosphate (ATP)IBA 10/2016
1	CateninsIBA 01/2016
1	hydroxide ionIBA 10/2014
1	Peptide YYIBA 09/2014
1	paricalcitol (Zemplar)FDA Link 09/2014
1	Hormones (Hormone)IBA 09/2014
1	Peptide Hormones (Polypeptide Hormones)IBA 09/2014

Therapy/Procedure

10	Therapeutics 01/2022 - 12/2004
2	Gastric Bypass (Roux-en-Y Gastric Bypass) 10/2019 - 09/2014
1	Enzyme Replacement Therapy 01/2022
1	Aftercare (After-Treatment) 12/2016
1	Operative Surgical Procedures 07/2015
1	Bariatric Surgery 09/2014